Properties and synthesis methods of amidinothiourea

Properties and synthesis methods of amidinothiourea

 

1. Properties of amidinothiourea:

English name: Amidinothiourea

English alias: Aminoiminoethyl thiourea; Guanylthiourea

Other names: 1-amidine-2-thiourea, 2-imino-4-sulfide biuret, Guthimine

Appearance: Milky white crystalline powder

Melting point: above 159.5 ℃ (complete melting)

Solubility: Soluble in methanol. Slightly soluble in water (about 3%). Insoluble in BTX class

Molecular formula: C2H6N4S

Molecular weight: 118.16

CAS NO.: 2114-02-5

EINECS NO.: 218-308-0

HS NO.:29309090

2. Use:

⑴It can be used as raw materials for pharmaceutical products. Itself has antihypoxic activity, used as an intermediate of motidine.

⑵ Can be used as metal surface treatment agent (rust prevention agent)

⑶ Can be used to remove residual chlorine in wastewater

⑷ It can be used as a pickling catalyst for steel plate substrate

⑸ Mixed with hydrogen peroxide, the water can be treated with antibacterial

3.Synthesis method of amidinothiourea:

Amidinothiourea is prepared from dicyandiamide, p-benzoquinone dioxime and hydrogen sulfide at room temperature with a yield of more than 90%. The method has the advantages of simple operation, high yield and low cost, and is an economical synthesis process suitable for industrial production.