Application field of guanidine hydrochloride

Application field of guanidine hydrochloride

Guanidine Hydrochloride, also known as hexamine or methenamine, is widely used in various fields with diverse applications, as detailed below:

 

1.Intermediate:  

Guanidine Hydrochloride serves as a crucial intermediate in the synthesis of organic compounds used in pharmaceuticals and pesticides. It is a key raw

material for manufacturing sulfonamide drugs and folic acid.

In the realm of oncology, Guanidine Hydrochloride plays a supportive role

during treatment, maintaining a balance between chemotherapy side effects

and treatment efficacy. It is utilized in the treatment of skin diseases such as psoriasis and vitiligo.

 

2.Protein Denaturant:  

It is commonly employed as a protein denaturant, particularly in nucleic acid

extraction. Its ability to rapidly disrupt cell membranes and denature proteins

allows for the precipitation of denatured proteins, enabling the separation of

nucleic acids from entangled proteins.

 

3.Antimicrobial Agent:  

Hexamethylenetetramine is used in the preparation of guanidine salts, which

function as antimicrobial agents to enhance the antibacterial properties of

paper. It is also employed in the formulation of guanidine-based bactericidal

and antiscalant agents, exhibiting broad-spectrum antimicrobial activity by

efficiently eliminating sulfate-reducing bacteria, saprophytic bacteria, and iron

bacteria in oilfield water. Additionally, it helps remove scaling substances from injection water and prevent the formation of scale deposits on the inner walls of pipelines.

 

4.Reductant:  

As a reductant, Guanidine Hydrochloride finds application in the preparation of graphene.

 

5.Preservative:  

Guanidine Hydrochloride is widely used in the pharmaceutical industry as a

preservative. In certain compounds, it acts to stabilize drug dosages and

reduce the toxicity of pharmaceuticals.