Pharmaceutical Grade Guanidine Hydrochloride
1. Chemical formula: CH6ClN3
2. Molecular weight: 95.53
3. CAS NO.: 50-01-1
4. EINECS NO.: 200-002-3
5. Melting point: 181℃
6. Water solubility: 1.354 g/cm3
- Product Introduction
Guanidine Hydrochloride BPG is used for A strong denaturant was extracted from cells for denaturation and renaturation of protein.
Downstream processing in biopharmaceutical manufacturing
Diagnostics (extraction buffers for the isolation of nucleic acids from biological specimens, test kits for viral RNA/DNA in clinical diagnostics)
mbth: guanidinine hydrochloride
alias: amidoformamidine hydrochloride
Chemical formula: CH6ClN3
Molecular weight: 95.53
CAS NO.: 50-01-1
EINECS NO.: 200-002-3
Melting point: 181℃
Water solubility: 1.354 g/cm3
Appearance: white crystal particles should be
Hazard symbol: description of hazardous
hazard: R22 R36/38.
Usage
Guanidine hydrochloride is produced by dicyandiamide and ammonia chloride as the main raw materials, used as pharmaceutical intermediates of organic synthesis, and is the important raw material to manufacture sulfa drugs, folic acid. sulfadiazine, sulfanilamide methyl pyridine. sulfanilamide dimethyl pyrimidine. In addition, it is used as a strong denaturant in the RNA cell extraction experiments. The Guanidine hydrochloride solution can dissolve protein, which leads to the destruction of the cellular structure and the nucleoprotein secondary structure; departing from the nucleic acid, the RNA enzymes can be inactivated by guanidine hydrochloride and other reducing agents.
The industrial-grade guanidine hydrochloride and 60% guanidine hydrochloride solution are the intermediates in making the pesticides, dyes, and organic synthesis. They also can be used as antistatic agents of the synthetic fiber.
|
Specification |
Pharmaceutic grade |
|
Appearance |
white crystalline powder |
|
Content ≥% |
99.8 |
|
Content of Ammonium Chloride ≤% |
0.05 |
|
Insoluble matter in water≤% |
0.02 |
|
Moisture≤% |
0.3 |
|
Ash conten≤% |
0.02 |
|
Water Solubility |
Clear and Colorless |
|
Melting poin℃ |
183-188 |
|
UV Absorption 260μm≤ |
0.04 |
|
UV Absorption 280μm≤ |
0.02 |
|
PH Coten(4% Aqueous Solution) |
6.4±0.2 |
|
Proportion d420 |
0.02 |
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