Guanidine Hydrochloride BPG

Guanidine Hydrochloride BPG is used for A strong denaturant was extracted from cells for denaturation and renaturation of protein.

Downstream processing in biopharmaceutical manufacturing

Diagnostics (extraction buffers for the isolation of nucleic acids from biological specimens, test kits for viral RNA/DNA in clinical diagnostics)

Chemical formula: CH6ClN3

Molecular weight: 95.53

CAS NO.: 50-01-1

EINECS NO.: 200-002-3

Melting point: 181℃

Water solubility: 1.354 g/cm3

Appearance: white crystal particles should be

Hazard symbol: description of hazardous

hazard: R22 R36/38.

Usage

Guanidine hydrochloride is produced by dicyandiamide and ammonia chloride as the main raw materials, used as pharmaceutical intermediates of organic synthesis, and is the important raw material to manufacture sulfa drugs, folic acid. sulfadiazine, sulfanilamide methyl pyridine. sulfanilamide dimethyl pyrimidine. In addition, it is used as a strong denaturant in the RNA cell extraction experiments. The Guanidine hydrochloride solution can dissolve protein, which leads to the destruction of the cellular structure and the nucleoprotein secondary structure; departing from the nucleic acid, the RNA enzymes can be inactivated by guanidine hydrochloride and other reducing agents.

The industrial-grade guanidine hydrochloride and 60% guanidine hydrochloride solution are the intermediates in making the pesticides, dyes and organic synthesis. They also can be used as antistatic agent of the synthetic fiber.

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