What is the solubility of Guanidine Carbonate in water?

Sep 30, 2025|

As a supplier of Guanidine Carbonate, I often receive inquiries about its solubility in water. Understanding the solubility of this chemical is crucial for various industries, including pharmaceuticals, agrochemicals, and polymer production. In this blog post, I will delve into the details of Guanidine Carbonate's solubility in water, its influencing factors, and practical applications.

Solubility Basics

Solubility refers to the maximum amount of a solute that can dissolve in a given amount of solvent at a specific temperature and pressure to form a homogeneous solution. For Guanidine Carbonate, the solvent of interest is water. At room temperature (around 25°C), Guanidine Carbonate exhibits relatively high solubility in water. It is an ionic compound, and its solubility can be attributed to the strong electrostatic interactions between the ions and water molecules. When dissolved in water, Guanidine Carbonate dissociates into guanidinium cations and carbonate anions, which are then surrounded by water molecules through a process called solvation.

Factors Affecting Solubility

Several factors can influence the solubility of Guanidine Carbonate in water.

Temperature

Temperature plays a significant role in solubility. Generally, the solubility of most solid solutes in water increases with rising temperature. This is because an increase in temperature provides more energy to break the intermolecular forces holding the solute particles together and allows them to interact more freely with the solvent molecules. For Guanidine Carbonate, as the temperature rises, more of it can dissolve in water. However, it's important to note that at extremely high temperatures, the compound may undergo decomposition, which can affect its solubility behavior.

pH

The pH of the solution can also impact the solubility of Guanidine Carbonate. Carbonate ions can react with hydrogen ions in acidic solutions to form carbonic acid, which then decomposes into carbon dioxide and water. In acidic conditions, the solubility of Guanidine Carbonate may increase as the carbonate ions are removed from the solution through this reaction. On the other hand, in basic solutions, the solubility may be relatively stable or slightly decrease due to the reduced availability of hydrogen ions for the reaction with carbonate ions.

Presence of Other Solutes

The presence of other solutes in the water can either enhance or reduce the solubility of Guanidine Carbonate. For example, if there are ions in the solution that can form insoluble salts with guanidinium or carbonate ions, the solubility of Guanidine Carbonate will decrease. Conversely, some solutes may have a salting - in effect, where they increase the solubility of the target compound by altering the solvent's properties.

Practical Solubility Data

Although specific solubility data can vary depending on the purity of the Guanidine Carbonate and the experimental conditions, at 25°C, approximately 60 - 70 grams of Guanidine Carbonate can dissolve in 100 milliliters of water. As the temperature increases to 50°C, the solubility can reach around 100 - 120 grams per 100 milliliters of water. These values are approximate and can be used as a general guide for industrial and laboratory applications.

Dicyandiamide powderRefined Guanidine Nitrate

Applications Related to Solubility

Pharmaceutical Industry

In the pharmaceutical industry, the solubility of Guanidine Carbonate in water is of great importance. It can be used as an intermediate in the synthesis of various drugs. The high solubility allows for easy incorporation into aqueous - based formulations, facilitating the production of tablets, capsules, and liquid medications. For example, it can be used in the synthesis of antiviral and antibacterial drugs, where its solubility ensures efficient delivery of the active ingredients in the body.

Agrochemical Industry

In agrochemicals, Guanidine Carbonate can be used as a raw material for the production of pesticides and fertilizers. Its solubility in water enables it to be easily formulated into sprayable solutions, which can be evenly distributed over crops. This ensures better absorption and effectiveness of the agrochemical products.

Polymer Industry

In the polymer industry, Guanidine Carbonate can act as a catalyst or a chain - extender. Its solubility in water allows for its uniform dispersion in polymer matrices during the synthesis process, leading to improved polymer properties such as mechanical strength and thermal stability.

Related Products

If you are interested in other guanidine - related products, we also offer Guanidine Thiocyanate Ultrapure, Refined Guanidine Nitrate, and Dicyandiamide Powder. These products also have unique solubility properties and find applications in various industries.

Conclusion

The solubility of Guanidine Carbonate in water is a key characteristic that determines its usability in multiple industries. Understanding the factors that affect its solubility, such as temperature, pH, and the presence of other solutes, is essential for optimizing its applications. Whether you are in the pharmaceutical, agrochemical, or polymer industry, the high solubility of Guanidine Carbonate in water provides numerous advantages.

If you are interested in purchasing Guanidine Carbonate or any of our related products, please feel free to contact us for a detailed discussion on your specific requirements. We are committed to providing high - quality products and excellent customer service.

References

  • Atkins, P. W., & de Paula, J. (2006). Physical Chemistry. Oxford University Press.
  • Haynes, W. M. (Ed.). (2014). CRC Handbook of Chemistry and Physics. CRC Press.
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